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  • procaine cas 59 46 1
  • procaine cas 59 46 1

Procaine wholesale

casno. : CAS 59-46-1

Specifications of Procaine

Chinese Name

Procaine

English Name

Procaine

Alias

Novocaine

English Alias

2-diethylaminoethyl 4-aminobenzoate
novocaine

CAS

59-46-1

EINECS

200-426-9

Chemical Formula

C13H20N2O2


Features of Procaine

It has less toxicity and is one of the commonly used local anesthetics. This drug is a short acting ester local anesthetic with low lipophilicity and weak penetration to mucous membrane. Generally, it is not used for surface anesthesia, but is often injected locally for infiltration anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia. It takes effect 1-3 minutes after injection, and can be maintained for 30-45 minutes. The maintenance time can be prolonged by 20% after adding adrenaline. Procaine can be hydrolyzed by esterase in plasma and converted into para aminobenzoic acid (PABA) and diethylaminoethanol. The former can resist the antibacterial effect of sulfonamides, so it should be avoided to use it together with sulfonamides. Procaine can also be used for local sealing of injured parts. Overuse can cause central nervous system and cardiovascular reactions. Sometimes it can cause allergic reaction, so skin allergy test should be done before use, but those with negative skin test can still have allergic reaction. For those allergic to this drug, chloroprocaine and lidocaine can be used instead.

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